Discover TripAdvisor's #1 Reno hotel and casino. Experience unmatched amenities, exciting casino action, elegant dining and a revitalizing spa. Atlantis Casino Awards View All Awards. Atlantis S. Virginia St. Reno, NV. A look at the 21 different casinos in Reno, NV., including the big six, busiest hotels and casinos in town. Reno's downtown casinos are conveniently located within a few steps of each Other casino resorts just outside of downtown are close to the area's airport and also 10Best Breweries and Taphouses in Reno and Virginia City, Nevada.